About 1000 Eastern. NASA TV and SpaceXchannel YouTube live streams, starting 1 hour and 30 minutes before T-0 respectively. 5,500 kg of cargo, including lab mice, and several experiments.

This will be their first launch from LC-39A, the pad used for Apollo 11 and the Space Shuttle.

And, SpaceX may have a visitor....

SpaceFlight Insider @SpaceflightIns
@POTUS will be visiting Florida's Space Coast Saturday, Feb. 18, the same day @SpaceX makes its first launch from historic Pad 39A. #CRS10
2:23 PM - 16 Feb 2017

Wonder if @POTUS will be Elons guest for the launch? Musk is on at least two White House advisory councils; strategic and manufacturing.